SNAP25 Rabbit Monoclonal Antibody (CAB2234)
- SKU:
- CAB2234
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | SNAP25 Rabbit Monoclonal Antibody |
SKU: | CAB2234 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 107-206 of human SNAP25 (P60880). |
Sequence: | NNQD GVVA SQPA RVVD EREQ MAIS GGFI RRVT NDAR ENEM DENL EQVS GIIG NLRH MALD MGNE IDTQ NRQI DRIM EKAD SNKT RIDE ANQR ATKM LGSG |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | SUP; RIC4; SEC9; SNAP; CMS18; RIC-4; SNAP-25; bA416N4.2; dJ1068F16.2; SNAP25 |
Positive Sample: | Mouse brain,Mouse eye,Rat brain,Rat eye |
Conjugate: | Unconjugated |
Cellular Localization: | Cell junction, Cell membrane, Cytoplasm, Lipid-anchor, perinuclear region, synapse, synaptosome. |
Calculated MW: | 23kDa |
Observed MW: | 25kDa |
Synaptic vesicle membrane docking and fusion is mediated by SNAREs (soluble N-ethylmaleimide-sensitive factor attachment protein receptors) located on the vesicle membrane (v-SNAREs) and the target membrane (t-SNAREs). The assembled v-SNARE/t-SNARE complex consists of a bundle of four helices, one of which is supplied by v-SNARE and the other three by t-SNARE. For t-SNAREs on the plasma membrane, the protein syntaxin supplies one helix and the protein encoded by this gene contributes the other two. Therefore, this gene product is a presynaptic plasma membrane protein involved in the regulation of neurotransmitter release. Two alternative transcript variants encoding different protein isoforms have been described for this gene.
Purification Method: | Affinity purification |
Gene ID: | 6616 |
Clone Number: | ARC0736 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |