SNAP25 Rabbit Polyclonal Antibody (CAB0986)
- SKU:
- CAB0986
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | SNAP25 Rabbit Polyclonal Antibody |
SKU: | CAB0986 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-206 of human SNAP25 (NP_570824.1). |
Sequence: | MAED ADMR NELE EMQR RADQ LADE SLES TRRM LQLV EESK DAGI RTLV MLDE QGEQ LERI EEGM DQIN KDMK EAEK NLTD LGKF CGLC VCPC NKLK SSDA YKKA WGNN QDGV VASQ PARV VDER EQMA ISGG FIRR VTND AREN EMDE NLEQ VSGI IGNL RHMA LDMG NEID TQNR QIDR IMEK ADSN KTRI DEAN QRAT KMLG SG |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | SUP; RIC4; SEC9; SNAP; CMS18; RIC-4; SNAP-25; bA416N4.2; dJ1068F16.2; SNAP25 |
Positive Sample: | SH-SY5Y,Mouse brain,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Cell junction, Cell membrane, Cytoplasm, Lipid-anchor, perinuclear region, synapse, synaptosome. |
Calculated MW: | 23kDa |
Observed MW: | 25kDa |
Synaptic vesicle membrane docking and fusion is mediated by SNAREs (soluble N-ethylmaleimide-sensitive factor attachment protein receptors) located on the vesicle membrane (v-SNAREs) and the target membrane (t-SNAREs). The assembled v-SNARE/t-SNARE complex consists of a bundle of four helices, one of which is supplied by v-SNARE and the other three by t-SNARE. For t-SNAREs on the plasma membrane, the protein syntaxin supplies one helix and the protein encoded by this gene contributes the other two. Therefore, this gene product is a presynaptic plasma membrane protein involved in the regulation of neurotransmitter release. Two alternative transcript variants encoding different protein isoforms have been described for this gene.
Purification Method: | Affinity purification |
Gene ID: | 6616 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |