null

SNAP23 Rabbit Polyclonal Antibody (CAB13909)

SKU:
CAB13909
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
  • Cell Biology Antibodies 4 Anti-SNAP23 Antibody CAB13909
  • Cell Biology Antibodies 4 Anti-SNAP23 Antibody CAB13909
  • Cell Biology Antibodies 4 Anti-SNAP23 Antibody CAB13909
  • Cell Biology Antibodies 4 Anti-SNAP23 Antibody CAB13909
€139 - €419
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:SNAP23 Rabbit Polyclonal Antibody
SKU:CAB13909
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-211 of human SNAP23 (NP_003816.2).
Sequence:MDNL SSEE IQQR AHQI TDES LEST RRIL GLAI ESQD AGIK TITM LDEQ KEQL NRIE EGLD QINK DMRE TEKT LTEL NKCC GLCV CPCN RTKN FESG KAYK TTWG DGGE NSPC NVVS KQPG PVTN GQLQ QPTT GAAS GGYI KRIT NDAR EDEM EENL TQVG SILG NLKD MALN IGNE IDAQ NPQI KRIT DKAD TNRD RIDI ANAR AKKL IDS
Tested Applications:WB IHC-P ELISA
Recommended Dilution:WB,1:500 - 1:2000 IHC-P,1:100 - 1:200
Synonyms:SNAP-23; SNAP23A; SNAP23B; HsT17016; SNAP23
Positive Sample:HeLa,Mouse kidney
Conjugate:Unconjugated
Cellular Localization:Cell junction, Cell membrane, Lipid-anchor, Peripheral membrane protein, synapse, synaptosome.
Calculated MW:23kDa
Observed MW:23kDa

Specificity of vesicular transport is regulated, in part, by the interaction of a vesicle-associated membrane protein termed synaptobrevin/VAMP with a target compartment membrane protein termed syntaxin. These proteins, together with SNAP25 (synaptosome-associated protein of 25 kDa), form a complex which serves as a binding site for the general membrane fusion machinery. Synaptobrevin/VAMP and syntaxin are believed to be involved in vesicular transport in most, if not all cells, while SNAP25 is present almost exclusively in the brain, suggesting that a ubiquitously expressed homolog of SNAP25 exists to facilitate transport vesicle/target membrane fusion in other tissues. The protein encoded by this gene is structurally and functionally similar to SNAP25 and binds tightly to multiple syntaxins and synaptobrevins/VAMPs. It is an essential component of the high affinity receptor for the general membrane fusion machinery and is an important regulator of transport vesicle docking and fusion. Two alternative transcript variants encoding different protein isoforms have been described for this gene.

Purification Method:Affinity purification
Gene ID:8773
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using SNAP23 Rabbit pAb (CAB13909) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 2min.

Related Products