The SNAI3 Polyclonal Antibody (CAB17854) is a research tool designed for the study of SNAI3, a transcription factor involved in the regulation of genes related to cell migration and invasion. This rabbit polyclonal antibody is highly specific and reactive with human samples, making it an ideal choice for researchers working in the fields of cancer biology, metastasis, and developmental biology.SNAI3, a member of the Snail family of transcription factors, plays a key role in the epithelial-mesenchymal transition (EMT) process, which is crucial for embryonic development and cancer progression. By targeting SNAI3 with this antibody, researchers can investigate its function in various cellular processes and pathways, providing valuable insights into the mechanisms underlying tumor metastasis and invasion.
Validated for use in Western blot applications, this antibody enables the detection and analysis of SNAI3 protein levels in different cell types and tissue samples. Its high reactivity and specificity make it a reliable tool for studying the regulation of gene expression by SNAI3 and its impact on cellular behavior. Researchers interested in understanding the molecular mechanisms of cancer progression and invasion will find this antibody essential for their studies.
Product Name:
SNAI3 Rabbit Polyclonal Antibody
SKU:
CAB17854
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 7-186 of human SNAI3 (NP_840101.1).
SNAI3 is a member of the SNAIL gene family, named for the Drosophila snail gene, which plays roles in mesodermal formation during embryogenesis (Katoh and Katoh, 2003 [PubMed 12579345]).
Purification Method:
Affinity purification
Gene ID:
333929
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using SNAI3 Rabbit pAb (CAB17854) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.