Slug Rabbit Polyclonal Antibody (CAB13352)
- SKU:
- CAB13352
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | Slug Rabbit Polyclonal Antibody |
SKU: | CAB13352 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 21-120 of human Slug (NP_003059.1). |
Sequence: | ELDT HTVI ISPY LYES YSMP VIPQ PEIL SSGA YSPI TVWT TAAP FHAQ LPNG LSPL SGYS SSLG RVSP PPPS DTSS KDHS GSES PISD EEER LQSK LSDP |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 |
Synonyms: | SLUG; WS2D; SLUGH; SLUGH1; SNAIL2; Slug |
Positive Sample: | Mouse brain,Rat lung,Rat spleen |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus. |
Calculated MW: | 30kDa |
Observed MW: | 30kDa |
This gene encodes a member of the Snail family of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Mutations in this gene may be associated with sporatic cases of neural tube defects.
Purification Method: | Affinity purification |
Gene ID: | 6591 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |