The SNAI1 Polyclonal Antibody (CAB5243) is a valuable tool for researchers studying SNAI1, a transcription factor known for its role in epithelial-mesenchymal transition (EMT) and cancer progression. This antibody, produced in rabbits, exhibits high specificity and sensitivity when detecting SNAI1 protein in human samples, making it an ideal choice for Western blot applications.SNAI1, also known as Snail, is a key regulator of EMT, a process essential for embryonic development and implicated in cancer metastasis. By targeting SNAI1, researchers can investigate its involvement in tumor progression, invasion, and therapy resistance.
This antibody enables precise detection and analysis of SNAI1 expression in various cell types, providing insights into its function and potential therapeutic targets in cancer research.The SNAI1 Polyclonal Antibody (CAB5243) opens up opportunities for exploring the molecular mechanisms underlying EMT and tumor progression, shedding light on potential strategies for targeted cancer therapies. Its reliable performance in Western blot applications makes it a valuable asset for studies aiming to unravel the complexities of SNAI1 signaling pathways and their impact on cancer development and progression.
Product Name:
Snail Rabbit Polyclonal Antibody
SKU:
CAB5243
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 200-267 of human SNAI1 (NP_005976.2).
The Drosophila embryonic protein snail is a zinc finger transcriptional repressor which downregulates the expression of ectodermal genes within the mesoderm. The nuclear protein encoded by this gene is structurally similar to the Drosophila snail protein, and is also thought to be critical for mesoderm formation in the developing embryo. At least two variants of a similar processed pseudogene have been found on chromosome 2.
Purification Method:
Affinity purification
Gene ID:
6615
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using Snail Rabbit pAb (CAB5243) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
