The Snaclec Rhodocytin Subunit Alpha Antibody (PACO53938) is a valuable tool for researchers studying the Rhodocytin protein, which is involved in platelet activation and aggregation. This polyclonal antibody, produced in rabbits, specifically targets the Rhodocytin subunit alpha, allowing for precise detection and analysis of this important protein.The antibody is highly reactive with human samples and has been validated for use in various applications, including Western blotting. By binding to the Rhodocytin subunit alpha, researchers can gain insights into its function in platelet biology and potential implications in diseases such as thrombosis and hemostasis disorders.
Overall, the Snaclec Rhodocytin Subunit Alpha Antibody is an essential tool for investigating the role of Rhodocytin in platelet function and exploring its therapeutic potential in related conditions. Its specificity and reliability make it a valuable asset for studies in the fields of hematology and cardiovascular research.
Antibody Name:
Snaclec rhodocytin subunit α Antibody (PACO53938)
Antibody SKU:
PACO53938
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:500-1:5000
Species Reactivity:
Calloselasma rhodostoma
Immunogen:
Recombinant Calloselasma rhodostoma Snaclec rhodocytin subunit α protein (1-136AA)
Western Blot. Positive WB detected in Recombinant protein. All lanes: Rhodocytin subunit alpha antibody at 3µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 31 kDa. Observed band size: 31 kDa.
Background:
Elicits platelet aggregation by the binding to the C-type lectin domain family 1 member B (CLEC1B/CLEC2). Binding leads to tyrosine phosphorylation in the cytoplasmic tail of CLEC1B, which promotes the binding of spleen tyrosine kinase (Syk), subsequent activation of PLC-gamma-2, and platelet activation and aggregation. Binding to GPIbα (GP1BA) and alpha-2/beta-1 (ITGA2/ITGB1) may also induce aggregation, but this is controversial.
Elicits platelet aggregation by the binding to the C-type lectin domain family 1 member B (CLEC1B/CLEC2). Binding leads to tyrosine phosphorylation in the cytoplasmic tail of CLEC1B, which promotes the binding of spleen tyrosine kinase (Syk), subsequent activation of PLC-gamma-2, and platelet activation and aggregation. Binding to GPIbalpha (GP1BA) and alpha-2/beta-1 (ITGA2/ITGB1) may also induce aggregation, but this is controversial.
