The SMYD4 Polyclonal Antibody (CAB7310) is a highly specific tool for researchers studying SMYD4, a protein known for its role in epigenetic regulation and cancer biology. This antibody, generated in rabbits, exhibits strong reactivity with human samples and is validated for use in Western blot applications.SMYD4 is a lysine methyltransferase that plays a critical role in regulating gene expression and chromatin structure. Dysregulation of SMYD4 has been linked to various cancers, making it a promising target for therapeutic intervention. The SMYD4 Polyclonal Antibody binds specifically to the SMYD4 protein, allowing for precise detection and analysis in a variety of cell types.
By studying SMYD4 and its functions, researchers can gain valuable insights into the mechanisms underlying cancer development and progression. This antibody enables detailed investigation into the role of SMYD4 in epigenetic modifications and its implications for tumorigenesis. Its versatility and reliability make it an essential tool for advancing research in the fields of cancer biology and epigenetics.
Product Name:
SMYD4 Rabbit Polyclonal Antibody
SKU:
CAB7310
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human SMYD4 (NP_443160.2).
WB,1:1000 - 1:5000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:100 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells
Synonyms:
ZMYND21; SMYD4
Positive Sample:
HeLa
Conjugate:
Unconjugated
Cellular Localization:
cytoplasm, nucleus
Calculated MW:
89kDa
Observed MW:
89kDa
Predicted to enable metal ion binding activity and methyltransferase activity. Involved in heart development. Predicted to be located in cytoplasm and nucleus.
Purification Method:
Affinity purification
Gene ID:
114826
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of lysates from HeLa cells, using SMYD4 Rabbit pAb (CAB7310) at 1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
