The SMUG1 Polyclonal Antibody (CAB10166) is a valuable tool for researchers studying SMUG1, a key enzyme involved in DNA repair and maintenance. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. It specifically targets the SMUG1 protein, allowing for accurate detection and analysis in a variety of cell types. SMUG1 is known for its role in base excision repair, a crucial process in maintaining genomic stability and preventing mutations that can lead to diseases like cancer.
Research into SMUG1 has implications for understanding the mechanisms of DNA damage and repair, as well as potential therapeutic approaches for diseases characterized by genomic instability. By studying the function and regulation of SMUG1, researchers can gain insights into how DNA repair processes contribute to overall cellular health and disease development.
Product Name:
SMUG1 Rabbit Polyclonal Antibody
SKU:
CAB10166
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human SMUG1 (NP_055126.1).
This gene encodes a protein that participates in base excision repair by removing uracil from single- and double-stranded DNA. Many alternatively spliced transcript variants exist for this gene; the full-length nature is known for some but not all of the variants.
Purification Method:
Affinity purification
Gene ID:
23583
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using SMUG1 antibody (CAB10166) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 30s.
