The SMU1 Polyclonal Antibody (CAB9110) is a vital tool for researchers studying the SMU1 protein, which plays a crucial role in pre-mRNA splicing. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the SMU1 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it ideal for investigations in molecular biology and genetics.SMU1, also known as Smu-1 suppressor of mec-8 and UNC-52 protein 1, is essential for the proper splicing of mRNA transcripts, ensuring accurate gene expression and protein production.
Dysregulation of mRNA splicing can lead to a range of diseases, including cancer and neurological disorders, making SMU1 a valuable target for research in these areas. Understanding the function and regulation of SMU1 is crucial for developing potential therapeutic interventions that target RNA processing pathways.
Product Name:
SMU1 Rabbit Polyclonal Antibody
SKU:
CAB9110
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human SMU1 (NP_060695.2).
Involved in mRNA splicing, via spliceosome. Located in nucleus. Part of U2-type precatalytic spliceosome.
Purification Method:
Affinity purification
Gene ID:
55234
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using SMU1 Rabbit pAb (CAB9110) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
