SMPD4 Rabbit Polyclonal Antibody (CAB15473)
- SKU:
- CAB15473
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | SMPD4 Rabbit Polyclonal Antibody |
SKU: | CAB15473 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 600-800 of human SMPD4 (NP_060421.2). |
Sequence: | ITQA KHTA KSIS DQCA ESPA GHSF LSWL GFSS MDTN GSYT ANDL DEMG QDSV RKTD EYLE KALE YLRQ IFRL SEAQ LRQF TLAL GTTQ DENG KKQL PDCI VGED GLIL TPLG RYQI INGL RRFE IEYQ GDPE LQPI RSYE IASL VRTL FRLS SAIN HRFA GQMA ALCS RDDF LGSF CRYH LTEP GLAS RHLL SPVG RRQV A |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:200 - 1:2000 IF/ICC,1:50 - 1:200 |
Synonyms: | SKNY; NET13; NEDMABA; NEDMEBA; NSMASE3; NSMASE-3; SMPD4 |
Positive Sample: | A-549 |
Conjugate: | Unconjugated |
Cellular Localization: | Endoplasmic reticulum membrane, Golgi apparatus membrane, Single-pass membrane protein. |
Calculated MW: | 98kDa |
Observed MW: | 100kDa |
The protein encoded by this gene is a sphingomyelinase that catalyzes the hydrolysis of membrane sphingomyelin to form phosphorylcholine and ceramide. This gene is activated by DNA damage, cellular stress, and tumor necrosis factor, but it is downregulated by wild-type p53. The encoded protein localizes to the endoplasmic reticulum and Golgi network.
Purification Method: | Affinity purification |
Gene ID: | 55627 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |