The SMPD2 Polyclonal Antibody (CAB1166) is a valuable tool for researchers studying sphingomyelin phosphodiesterase 2 (SMPD2), an enzyme involved in sphingolipid metabolism and cell signaling pathways. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications.SMPD2 plays a crucial role in regulating cellular processes such as apoptosis, cell growth, and immune response. By targeting SMPD2 with this antibody, researchers can detect and analyze the protein in various cell types, providing insights into its functions and potential therapeutic applications.
The SMPD2 Polyclonal Antibody is a valuable asset for studies in molecular biology, biochemistry, and pharmacology, offering a deeper understanding of sphingolipid metabolism and its implications in diseases such as cancer, neurodegenerative disorders, and metabolic syndromes. Its high specificity and reliability make it an essential tool for researchers seeking to unravel the complex functions of SMPD2 in cellular processes and disease pathogenesis.
Product Name:
SMPD2 Rabbit Polyclonal Antibody
SKU:
CAB1166
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 150-250 of human SMPD2 (NP_003071.2).
This gene encodes a protein which was initially identified as a sphingomyelinase based on sequence similarity between bacterial sphingomyelinases and a yeast protein. Subsequent studies showed that its biological function is less likely to be as a sphingomyelinase and instead as a lysophospholipase.
Purification Method:
Affinity purification
Gene ID:
6610
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using SMPD2 Rabbit pAb (CAB1166) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
