SMPD1/ASM Rabbit Polyclonal Antibody (CAB16263)
- SKU:
- CAB16263
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | SMPD1/ASM Rabbit Polyclonal Antibody |
SKU: | CAB16263 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 70-340 of human SMPD1 / ASM (NP_000534.3). |
Sequence: | PARL HRIV PRLR DVFG WGNL TCPI CKGL FTAI NLGL KKEP NVAR VGSV AIKL CNLL KIAP PAVC QSIV HLFE DDMV EVWR RSVL SPSE ACGL LLGS TCGH WDIF SSWN ISLP TVPK PPPK PPSP PAPG APVS RILF LTDL HWDH DYLE GTDP DCAD PLCC RRGS GLPP ASRP GAGY WGEY SKCD LPLR TLES LLSG LGPA GPFD MVYW TGDI PAHD VWHQ TRQD QLRA LTTV TALV RKFL GPVP VYPA VGNH ESTP VNSF PPPF IEGN HSS |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:100 - 1:500 IF/ICC,1:50 - 1:100 |
Synonyms: | ASM; NPD; ASMASE; SMPD1 / ASM |
Positive Sample: | Mouse liver,Rat liver,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Lysosome. |
Calculated MW: | 70kDa |
Observed MW: | 75kDa |
The protein encoded by this gene is a lysosomal acid sphingomyelinase that converts sphingomyelin to ceramide. The encoded protein also has phospholipase C activity. Defects in this gene are a cause of Niemann-Pick disease type A (NPA) and Niemann-Pick disease type B (NPB). Multiple transcript variants encoding different isoforms have been identified.
Purification Method: | Affinity purification |
Gene ID: | 6609 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |