The Smoothelin Polyclonal Antibody (CAB6745) is a high-quality antibody designed for research involving Smoothelin, a protein involved in smooth muscle contraction and relaxation. This antibody, raised in rabbits, is highly specific and reactive with human samples, making it ideal for use in immunohistochemistry and Western blot applications.Smoothelin is a key marker for smooth muscle cells and is important in studying various physiological processes such as vascular function and gastrointestinal motility. The Smoothelin Polyclonal Antibody binds specifically to Smoothelin, enabling precise detection and analysis in a variety of tissue types.
Its versatility and specificity make it a valuable tool for researchers in the fields of cardiology, gastroenterology, and vascular biology.By understanding the role of Smoothelin in smooth muscle function, researchers can gain insights into diseases such as cardiovascular disorders, gastrointestinal diseases, and uterine abnormalities. The Smoothelin Polyclonal Antibody provides researchers with a reliable and accurate tool to further explore the function and regulation of Smoothelin in health and disease.
Product Name:
SMTN Rabbit Polyclonal Antibody
SKU:
CAB6745
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 65-325 of human SMTN (NP_001193946.1).
This gene encodes a structural protein that is found exclusively in contractile smooth muscle cells. It associates with stress fibers and constitutes part of the cytoskeleton. This gene is localized to chromosome 22q12.3, distal to the TUPLE1 locus and outside the DiGeorge syndrome deletion. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.
Purification Method:
Affinity purification
Gene ID:
6525
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using SMTN antibody (CAB6745) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 5min.
