The SMNDC1 Polyclonal Antibody (CAB0681) is a vital tool for researchers studying SMNDC1, a key player in pre-mRNA splicing and mRNA export processes. This antibody, produced in rabbits, demonstrates high reactivity with human samples and is validated for use in Western blot applications. By binding specifically to the SMNDC1 protein, this antibody enables precise detection and analysis in a variety of cell types, making it ideal for studies in molecular biology and gene expression.SMNDC1, also referred to as survival motor neuron domain containing 1, plays a crucial role in RNA processing and gene regulation.
Dysregulation of SMNDC1 has been implicated in various diseases, including spinal muscular atrophy and cancer. By investigating the function of SMNDC1, researchers can gain valuable insights into the mechanisms of these conditions, potentially leading to the development of novel therapeutic strategies.Overall, the SMNDC1 Polyclonal Antibody (CAB0681) is a valuable tool for researchers aiming to unravel the intricate processes of RNA metabolism and gene expression, ultimately contributing to advancements in biomedical research and potentially uncovering new treatment options for a range of diseases.
Product Name:
SMNDC1 Rabbit Polyclonal Antibody
SKU:
CAB0681
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-238 of human SMNDC1 (NP_005862.1).
This gene is a paralog of SMN1 gene, which encodes the survival motor neuron protein, mutations in which are cause of autosomal recessive proximal spinal muscular atrophy. The protein encoded by this gene is a nuclear protein that has been identified as a constituent of the spliceosome complex. This gene is differentially expressed, with abundant levels in skeletal muscle, and may share similar cellular function as the SMN1 gene.
Purification Method:
Affinity purification
Gene ID:
10285
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using SMNDC1 antibody (CAB0681) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
