SMG6 Rabbit Polyclonal Antibody (CAB10141)
- SKU:
- CAB10141
- Product Type:
- Antibody
- Reactivity:
- Human
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | SMG6 Rabbit Polyclonal Antibody |
SKU: | CAB10141 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1160-1419 of human SMG6 (NP_060045.4). |
Sequence: | PDTM GKEM GSQE GTRL EDEE EDVV IEDF EEDS EAEG SGGE DDIR ELRA KKLA LARK IAEQ QRRQ EKIQ AVLE DHSQ MRQM ELEI RPLF LVPD TNGF IDHL ASLA RLLE SRKY ILVV PLIV INEL DGLA KGQE TDHR AGGY ARVV QEKA RKSI EFLE QRFE SRDS CLRA LTSR GNEL ESIA FRSE DITG QLGN NDDL ILSC CLHY CKDK AKDF MPAS KEEP IRLL REVV LLTD DRNL RVKA LTRN VPVR DIPA FLTW AQVG |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | EST1A; SMG-6; hEST1A; C17orf31; hSMG5/7a; SMG6 |
Positive Sample: | HeLa,Jurkat,SW620,Rat liver |
Conjugate: | Unconjugated |
Cellular Localization: | Chromosome, Cytoplasm, Nucleus, cytosol, nucleolus, telomere. |
Calculated MW: | 160kDa |
Observed MW: | 210kDa |
This gene encodes a component of the telomerase ribonucleoprotein complex responsible for the replication and maintenance of chromosome ends. The encoded protein also plays a role in the nonsense-mediated mRNA decay (NMD) pathway, providing the endonuclease activity near the premature translation termination codon that is needed to initiate NMD. Alternatively spliced transcript variants encoding distinct protein isoforms have been described.
Purification Method: | Affinity purification |
Gene ID: | 23293 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |