SMC3 Rabbit Polyclonal Antibody (CAB18402)
- SKU:
- CAB18402
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | SMC3 Rabbit Polyclonal Antibody |
SKU: | CAB18402 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 909-1199 of human SMC3 (NP_005436.1). |
Sequence: | KEHM DAIN HDTK ELEK MTNR QGML LKKK EECM KKIR ELGS LPQE AFEK YQTL SLKQ LFRK LEQC NTEL KKYS HVNK KALD QFVN FSEQ KEKL IKRQ EELD RGYK SIME LMNV LELR KYEA IQLT FKQV SKNF SEVF QKLV PGGK ATLV MKKG DVEG SQSQ DEGE GSGE SERG SGSQ SSVP SVDQ FTGV GIRV SFTG KQGE MREM QQLS GGQK SLVA LALI FAIQ KCDP APFY LFDE IDQA LDAQ HRKA VSDM IMEL AVHA QFIT TTFR PELL ESAD KFYG VKFR NKVS HID |
Tested Applications: | WB IP ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IP,0.5μg-4μg antibody for 400μg-600μg extracts of whole cells |
Synonyms: | BAM; BMH; HCAP; CDLS3; CSPG6; SMC3L1; SMC3 |
Positive Sample: | U-87MG,Jurkat,HeLa,Mouse testis,Mouse spleen |
Cellular Localization: | cytosol, mitotic spindle pole, nuclear matrix, nucleoplasm, nucleus |
Calculated MW: | 142kDa |
Observed MW: | 142kDa |
This gene belongs to the SMC3 subfamily of SMC proteins. The encoded protein occurs in certain cell types as either an intracellular, nuclear protein or a secreted protein. The nuclear form, known as structural maintenance of chromosomes 3, is a component of the multimeric cohesin complex that holds together sister chromatids during mitosis, enabling proper chromosome segregation. Post-translational modification of the encoded protein by the addition of chondroitin sulfate chains gives rise to the secreted proteoglycan bamacan, an abundant basement membrane protein.
Purification Method: | Affinity purification |
Gene ID: | 9126 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |