The SMC2 Polyclonal Antibody (CAB17867) is a valuable tool for research involving SMC2, a protein involved in chromosome condensation and segregation during cell division. This antibody, raised in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. It specifically binds to SMC2, allowing for the detection and analysis of this protein in various cell types.SMC2 is a key player in the maintenance of genome stability and proper chromosome separation, making it a crucial target for study in the fields of cell biology and cancer research.
Dysregulation of SMC2 has been implicated in various diseases, including cancer and developmental disorders, highlighting the importance of understanding its function and regulation.By using the SMC2 Polyclonal Antibody in research, scientists can further elucidate the role of SMC2 in cellular processes and potentially uncover new therapeutic targets for the treatment of diseases associated with SMC2 dysfunction.
Product Name:
SMC2 Rabbit Polyclonal Antibody
SKU:
CAB17867
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 700-900 of human SMC2 (NP_006435.2).
Predicted to enable ATP binding activity; chromatin binding activity; and single-stranded DNA binding activity. Involved in mitotic chromosome condensation. Located in condensed chromosome; cytoplasm; and nuclear lumen. Part of condensin complex.
Purification Method:
Affinity purification
Gene ID:
10592
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using SMC2 Rabbit pAb (CAB17867) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
