The SMARCD2 Polyclonal Antibody (CAB12104) is a valuable tool for researchers studying SMARCD2, a protein involved in chromatin remodeling and gene regulation. Raised in rabbits, this antibody is highly specific to human samples and has been validated for use in Western blot applications. It binds to the SMARCD2 protein, allowing for the detection and analysis of this important molecule in various cell types.SMARCD2, also known as BAF60B, is a subunit of the SWI/SNF chromatin remodeling complex, which plays a critical role in controlling gene expression and cell fate determination. Dysregulation of SMARCD2 has been implicated in various diseases, including cancer and developmental disorders.
By studying SMARCD2 with this antibody, researchers can gain valuable insights into its role in chromatin remodeling and gene regulation, leading to a better understanding of its impacts on health and disease.Overall, the SMARCD2 Polyclonal Antibody (CAB12104) is a versatile tool for researchers interested in exploring the functions of SMARCD2 in various biological processes, making it an essential component of studies in molecular biology, genetics, and disease mechanisms.
Product Name:
SMARCD2 Rabbit Polyclonal Antibody
SKU:
CAB12104
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 454-531 of human SMARCD2 (NP_001091896.1).
The protein encoded by this gene is a member of the SWI/SNF family of proteins, whose members display helicase and ATPase activities and which are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI and has sequence similarity to the yeast Swp73 protein. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
6603
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from Rat thymus, using SMARCD2 Rabbit pAb (CAB12104) at 1:600 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
