The SMARCC2 Polyclonal Antibody (CAB1967) is a valuable tool for researchers studying SMARCC2, a key component of the SWI/SNF chromatin remodeling complex. This antibody is generated in rabbits and has high reactivity with human samples, making it ideal for use in Western blot applications. By binding to the SMARCC2 protein, this antibody enables accurate detection and analysis in various cell types, providing valuable insights into chromatin remodeling processes.SMARCC2, also known as BAF170, plays a crucial role in regulating gene expression by modulating chromatin structure.
Dysregulation of SMARCC2 has been implicated in various diseases, including cancer and developmental disorders. Understanding the function of SMARCC2 is essential for unraveling the mechanisms underlying these conditions and identifying potential therapeutic targets.By utilizing the SMARCC2 Polyclonal Antibody in their research, scientists can further elucidate the role of SMARCC2 in chromatin remodeling and gene regulation, paving the way for advancements in fields such as cancer biology and developmental genetics.
Product Name:
SMARCC2 Rabbit Polyclonal Antibody
SKU:
CAB1967
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 150-250 of human SMARCC2 (NP_620706.1).
The protein encoded by this gene is a member of the SWI/SNF family of proteins, whose members display helicase and ATPase activities and which are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI and contains a predicted leucine zipper motif typical of many transcription factors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
6601
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates, using SMARCC2 Rabbit pAb (CAB1967) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
