The SMARCC1/BAF155 Rabbit Monoclonal Antibody (CAB4275) is a valuable tool for researchers studying SMARCC1/BAF155, a key component of the SWI/SNF chromatin remodeling complex. This antibody, produced in rabbits, exhibits high reactivity and specificity with human samples, making it an ideal choice for Western blot applications. By targeting the SMARCC1/BAF155 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it essential for studies in epigenetics, gene regulation, and cancer research.SMARCC1/BAF155 is essential for regulating gene expression by remodeling chromatin structure, influencing transcriptional activities, and modulating cellular processes.
Dysregulation of SMARCC1/BAF155 has been linked to various diseases, including cancer, developmental disorders, and neurological conditions. Therefore, understanding the function and activity of SMARCC1/BAF155 is crucial for unraveling its role in disease pathogenesis and identifying potential therapeutic targets.With its superior performance and proven effectiveness in research applications, the SMARCC1/BAF155 Rabbit Monoclonal Antibody (CAB4275) offers researchers a reliable tool for investigating the complex mechanisms involving SMARCC1/BAF155 and its impact on cellular functions and disease development.
Product Name:
SMARCC1/BAF155 Rabbit Monoclonal Antibody
SKU:
CAB4275
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 700-800 of human SMARCC1/BAF155 (Q92922).
Sequence:
AFLA SVVD PRVA SAAA KAAL EEFS RVRE EVPL ELVE AHVK KVQE AARA SGKV DPTY GLES SCIA GTGP DEPE KLEG AEEE KMEA DPDG QQPE KAEN KVEN E
Tested Applications:
WBIF/ICCChIPELISA
Recommended Dilution:
WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200 ChIP,5μg antibody for 10μg-15μg of Chromatin
Synonyms:
HYC5; Rsc8; SRG3; SWI3; BAF155; CRACC1; 55
Positive Sample:
HeLa,HepG2,Mouse brain,Mouse testis
Conjugate:
Unconjugated
Cellular Localization:
Nucleus.
Calculated MW:
123kDa
Observed MW:
155kDa
The protein encoded by this gene is a member of the SWI/SNF family of proteins, whose members display helicase and ATPase activities and which are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI and contains a predicted leucine zipper motif typical of many transcription factors.
Purification Method:
Affinity purification
Gene ID:
6599
Clone Number:
ARC0948
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using SMARCC1/BAF155 Rabbit mAb (CAB4275) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3min.
