The SMARCA1 Polyclonal Antibody (CAB5850) is a valuable tool for research involving the SMARCA1 protein, a member of the SWI/SNF chromatin remodeling complex. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding to the SMARCA1 protein, this antibody allows for the detection and analysis of SMARCA1 in various cell types, making it an excellent choice for studies in epigenetics and cancer research.SMARCA1, also known as SNF2L, is a key player in chromatin remodeling processes that regulate gene expression. Dysregulation of SMARCA1 has been implicated in various diseases, including cancer, where it can impact cell proliferation, differentiation, and metastasis.
By studying the function of SMARCA1, researchers can gain insights into the mechanisms underlying these diseases and potentially identify new therapeutic targets for intervention.Overall, the SMARCA1 Polyclonal Antibody is a valuable tool for investigating the role of SMARCA1 in chromatin remodeling and its implications for human health. Its high specificity and sensitivity make it an essential resource for advancing our understanding of epigenetic regulation and developing new strategies for combating diseases driven by chromatin dysregulation.
Product Name:
SMARCAD1 Rabbit Polyclonal Antibody
SKU:
CAB5850
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human SMARCAD1 (NP_001121901.1).
This gene encodes a member of the SNF subfamily of helicase proteins. The encoded protein plays a critical role in the restoration of heterochromatin organization and propagation of epigenetic patterns following DNA replication by mediating histone H3/H4 deacetylation. Mutations in this gene are associated with adermatoglyphia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Purification Method:
Affinity purification
Gene ID:
56916
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Immunofluorescence analysis of A549 cells using SMARCAD1 antibody (CAB5850). Blue: DAPI for nuclear staining.
