The SMARCA1 Polyclonal Antibody (CAB10248) is a valuable tool for researchers studying SMARCA1, a key protein involved in chromatin remodeling and gene regulation. This antibody, derived from rabbit serum, exhibits high specificity for human samples and has been validated for use in Western blot applications. By binding to the SMARCA1 protein, this antibody enables precise detection and analysis in a variety of cell types, making it an essential reagent for studies in molecular biology and cancer research.SMARCA1, also known as SNF2L, plays a crucial role in controlling gene expression by modulating chromatin structure.
Dysregulation of SMARCA1 has been linked to various diseases, including cancer and developmental disorders, highlighting its importance in cellular function. By investigating the functions of SMARCA1, researchers can gain insights into the mechanisms underlying these diseases and potentially identify new therapeutic targets for intervention. Harnessing the power of the SMARCA1 Polyclonal Antibody is key to advancing our understanding of gene regulation and its impact on human health.
Product Name:
SMARCA1 Rabbit Polyclonal Antibody
SKU:
CAB10248
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human SMARCA1 (NP_003060.2).
This gene encodes a member of the SWI/SNF family of proteins. The encoded protein is an ATPase which is expressed in diverse tissues and contributes to the chromatin remodeling complex that is involved in transcription. The protein may also play a role in DNA damage, growth inhibition and apoptosis of cancer cells. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
6594
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using SMARCA1 Rabbit pAb (CAB10248) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 15s.
