Description
Product Name: | Smad6 Polyclonal Antibody |
SKU: | CAB24035 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 231-330 of human Smad6 (NP_005576.3). |
Sequence: | RWPD LQHA VELK PLCG CHSF AAAA DGPT VCCN PYHF SRLC GPES PPPP YSRL SPRD EYKP LDLS DSTL SYTE TEAT NSLI TAPG EFSD ASMS PDAT KPSH |
Tested Applications: | WB |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | AOVD2; MADH6; MADH7; HsT17432; Smad6 |
Positive Sample: | HeLa,A549 |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus. |
Calculated MW: | 53kDa |
Observed MW: | 70kDa |
The protein encoded by this gene belongs to the SMAD family of proteins, which are related to Drosophila 'mothers against decapentaplegic' (Mad) and C. elegans Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions in the negative regulation of BMP and TGF-beta/activin-signalling. Multiple transcript variants have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 4091 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |