The Smad5 Polyclonal Antibody (CAB14023) is a valuable tool for researchers studying Smad5, a critical protein involved in the TGF-β signaling pathway. This antibody, raised in rabbits, is highly specific and reacts strongly with human samples, making it ideal for use in Western blot applications. By binding to Smad5, this antibody enables the detection and analysis of Smad5 in various cell types, providing invaluable insights into cell signaling pathways and regulatory mechanisms.Smad5 is a key player in cell growth, differentiation, and development, making it a pivotal target for research in developmental biology, cancer biology, and tissue regeneration.
By studying the expression and function of Smad5, researchers can uncover novel mechanisms underlying cell behavior and potentially identify new therapeutic targets for diseases such as cancer and developmental disorders.Overall, the Smad5 Polyclonal Antibody (CAB14023) offers researchers a reliable tool for investigating the role of Smad5 in various physiological and pathological processes, paving the way for advancements in basic science and potential therapeutic interventions.
Product Name:
Smad5 Rabbit Polyclonal Antibody
SKU:
CAB14023
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 200-300 of human Smad5 (NP_005894.3).
The protein encoded by this gene is involved in the transforming growth factor beta signaling pathway that results in an inhibition of the proliferation of hematopoietic progenitor cells. The encoded protein is activated by bone morphogenetic proteins type 1 receptor kinase, and may be involved in cancer. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
4090
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using Smad5 Rabbit pAb (CAB14023) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
