The SLU7 Polyclonal Antibody (CAB17614) is a valuable tool for researchers studying SLU7, a critical splicing factor involved in pre-mRNA splicing regulation. This antibody, developed using rabbits, exhibits high reactivity with human samples and is specifically validated for use in Western blot applications. By targeting the SLU7 protein, this antibody enables precise detection and analysis in a variety of cell types, making it a versatile tool for investigations in molecular biology and gene expression research.
SLU7 is an essential factor in spliceosome assembly, playing a pivotal role in ensuring accurate RNA splicing process. Dysregulation of SLU7 function has been linked to various diseases, including cancer and genetic disorders, highlighting its importance in maintaining cellular homeostasis. Research on SLU7 can provide valuable insights into the mechanisms of gene expression and RNA processing, offering potential targets for therapeutic interventions in disease contexts.
Product Name:
SLU7 Rabbit Polyclonal Antibody
SKU:
CAB17614
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human SLU7 (NP_006416.3).
Pre-mRNA splicing occurs in two sequential transesterification steps. The protein encoded by this gene is a splicing factor that has been found to be essential during the second catalytic step in the pre-mRNA splicing process. It associates with the spliceosome and contains a zinc knuckle motif that is found in other splicing factors and is involved in protein-nucleic acid and protein-protein interactions.
Purification Method:
Affinity purification
Gene ID:
10569
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using SLU7 Rabbit pAb (CAB17614) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
