UniProt Protein Function: | SLITRK5: Suppresses neurite outgrowth. Belongs to the SLITRK family.Protein type: Membrane protein, integralChromosomal Location of Human Ortholog: 13q31.2Cellular Component: integral to membrane; receptor complexBiological Process: skin development; grooming behavior; synaptic transmission; response to xenobiotic stimulus; axonogenesis; striatum development; dendrite morphogenesis; adult behavior |
UniProt Protein Details: | |
NCBI Summary: | Members of the SLITRK family, such as SLITRK5, are integral membrane proteins with 2 N-terminal leucine-rich repeat (LRR) domains similar to those of SLIT proteins (see SLIT1; MIM 603742). Most SLITRKs, including SLITRK5, also have C-terminal regions that share homology with neurotrophin receptors (see NTRK1; MIM 191315). SLITRKs are expressed predominantly in neural tissues and have neurite-modulating activity (Aruga et al., 2003 [PubMed 14557068]).[supplied by OMIM, Mar 2008] |
UniProt Code: | O94991 |
NCBI GenInfo Identifier: | 46397810 |
NCBI Gene ID: | 26050 |
NCBI Accession: | O94991.2 |
UniProt Secondary Accession: | O94991 |
UniProt Related Accession: | O94991 |
Molecular Weight: | |
NCBI Full Name: | SLIT and NTRK-like protein 5 |
NCBI Synonym Full Names: | SLIT and NTRK like family member 5 |
NCBI Official Symbol: | SLITRK5Â Â |
NCBI Official Synonym Symbols: | LRRC11; bA364G4.2Â Â |
NCBI Protein Information: | SLIT and NTRK-like protein 5 |
UniProt Protein Name: | SLIT and NTRK-like protein 5 |
UniProt Synonym Protein Names: | Leucine-rich repeat-containing protein 11 |
Protein Family: | |
UniProt Gene Name: | SLITRK5Â Â |
UniProt Entry Name: | SLIK5_HUMAN |