The SLITRK3 Polyclonal Antibody (PACO29984) is a valuable tool for research involving SLITRK3, a protein involved in neural development and synaptic function. This antibody, raised in rabbits, exhibits high reactivity with human samples and is validated for use in various applications, including Western blot and immunofluorescence. By specifically binding to the SLITRK3 protein, this antibody allows for the detection and analysis of SLITRK3 expression in different cell types, making it ideal for studies in neuroscience and neurodevelopmental disorders.SLITRK3 is known to play a crucial role in neuronal connectivity and communication, making it a key target for research into neurological conditions such as autism spectrum disorders, schizophrenia, and epilepsy.
By understanding the function and regulation of SLITRK3, researchers can gain valuable insights into the underlying mechanisms of these disorders and potentially identify new therapeutic targets for treatment.Overall, the SLITRK3 Polyclonal Antibody (PACO29984) provides researchers with a powerful tool to investigate the role of SLITRK3 in neural development and function, advancing our understanding of neurobiology and offering new possibilities for the development of treatments for neurological disorders.
Antibody Name:
SLITRK3 Antibody (PACO29984)
Antibody SKU:
PACO29984
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA
Recommended Dilutions:
Species Reactivity:
Human
Immunogen:
Recombinant Human SLIT and NTRK-like protein 3 protein (746-977AA)
SLITRK3: Suppresses neurite outgrowth. Belongs to the SLITRK family.Protein type: Membrane protein, integral; Cell surfaceChromosomal Location of Human Ortholog: 3q26.1Cellular Component: integral to membraneBiological Process: axonogenesis
UniProt Protein Details:
NCBI Summary:
Members of the SLITRK family, such as SLITRK3, are integral membrane proteins with 2 N-terminal leucine-rich repeat (LRR) domains similar to those of SLIT proteins (see SLIT1; MIM 603742). Most SLITRKs, including SLITRK3, also have C-terminal regions that share homology with neurotrophin receptors (see NTRK1; MIM 191315). SLITRKs are expressed predominantly in neural tissues and have neurite-modulating activity (Aruga et al., 2003 [PubMed 14557068]).[supplied by OMIM, Mar 2008]
