The SLIT1 Polyclonal Antibody (CAB16430) is a valuable tool for researchers studying SLIT1, a protein involved in neuronal development and axon guidance. This antibody, generated in rabbits, demonstrates high reactivity with human samples and is specifically validated for use in immunohistochemistry and Western blotting applications. By binding to the SLIT1 protein, this antibody enables precise detection and analysis in a variety of cell types, making it ideal for neurological research and neurodevelopmental disorders.
SLIT1 is a crucial player in the guidance of neuronal axons during development, helping to establish proper connections and circuitry in the nervous system. Dysregulation of SLIT1 has been linked to conditions such as autism spectrum disorders and other neurodevelopmental abnormalities. By understanding the function and regulation of SLIT1, researchers can gain insights into the mechanisms underlying these disorders and potentially identify new therapeutic targets for intervention.
Product Name:
SLIT1 Rabbit Polyclonal Antibody
SKU:
CAB16430
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1315-1534 of human SLIT1 (NP_003052.2).
Enables Roundabout binding activity. Involved in axon extension involved in axon guidance; motor neuron axon guidance; and negative chemotaxis. Predicted to be located in extracellular region. Predicted to be active in extracellular space.
Purification Method:
Affinity purification
Gene ID:
6585
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from 293T cells, using SLIT1 Rabbit pAb (CAB16430) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3min.
