The SLIRP Polyclonal Antibody (CAB15524) is specifically designed for research involving SLIRP, a crucial protein involved in mitochondrial function and RNA metabolism. This antibody, raised in rabbits, is highly reactive with human samples and has been validated for use in various applications such as Western blot and immunofluorescence.SLIRP, also known as SRA Stem-Loop Interacting RNA Binding Protein, is essential for maintaining mitochondrial homeostasis and regulating gene expression.
Its role in RNA metabolism highlights its importance in cellular processes and its potential implications in various diseases, including cancer and metabolic disorders. By targeting SLIRP with this antibody, researchers can investigate its functions and interactions in different cell types, providing valuable insights into mitochondrial biology and potential therapeutic targets.
Product Name:
SLIRP Rabbit Polyclonal Antibody
SKU:
CAB15524
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human SLIRP (NP_112487.1).
Steroid receptor RNA activator (SRA, or SRA1; MIM 603819) is a complex RNA molecule containing multiple stable stem-loop structures that functions in coactivation of nuclear receptors. SLIRP interacts with stem-loop structure-7 of SRA (STR7) and modulates nuclear receptor transactivation (Hatchell et al., 2006 [PubMed 16762838]).
Purification Method:
Affinity purification
Gene ID:
81892
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using SLIRP Rabbit pAb (CAB15524) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
