SLCO1B1 Rabbit Polyclonal Antibody (CAB17082)
- SKU:
- CAB17082
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
Product Name: | SLCO1B1 Rabbit Polyclonal Antibody |
SKU: | CAB17082 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 597-691 of human SLCO1B1 (NP_006437.3). |
Sequence: | TTCI KWST NNCG TRGS CRTY NSTS FSRV YLGL SSML RVSS LVLY IILI YAMK KKYQ EKDI NASE NGSV MDEA NLES LNKN KHFV PSAG ADSE THC |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | LST1; HBLRR; LST-1; OATP2; OATPC; OATP-C; OATP1B1; SLC21A6; SLCO1B1 |
Positive Sample: | HepG2,MCF7,Mouse liver,Rat liver |
Cellular Localization: | Basolateral cell membrane, Multi-pass membrane protein. |
Calculated MW: | 76kDa |
Observed MW: | 76kDa |
This gene encodes a liver-specific member of the organic anion transporter family. The encoded protein is a transmembrane receptor that mediates the sodium-independent uptake of numerous endogenous compounds including bilirubin, 17-beta-glucuronosyl estradiol and leukotriene C4. This protein is also involved in the removal of drug compounds such as statins, bromosulfophthalein and rifampin from the blood into the hepatocytes. Polymorphisms in the gene encoding this protein are associated with impaired transporter function.
Purification Method: | Affinity purification |
Gene ID: | 10599 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |