null

SLC9A7 Antibody (PACO18908)

SKU:
PACO18908
Product Type:
Antibody
Reactivity:
Human
Mouse
Host Species:
Rabbit
Isotype:
IgG
Applications:
ELISA
IHC
Antibody Type:
Polyclonal Antibody
Conjugation:
Unconjugated
€339

Description

system_update_altDatasheetsystem_update_altMSDS

SLC9A7 Antibody (PACO18908)

The SLC9A7 Antibody (PAC018908) is a polyclonal antibody designed for research involving SLC9A7, a member of the SLC9 sodium/hydrogen exchanger family. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. It binds to the SLC9A7 protein, allowing for the detection and analysis of this protein in various cell types.SLC9A7 is known to play a role in the regulation of intracellular pH and ion homeostasis, making it a crucial player in cellular function.

Research into SLC9A7 can provide insights into its involvement in diseases such as cancer, neurological disorders, and cardiovascular conditions. By understanding the function of SLC9A7, researchers can potentially identify therapeutic targets for these diseases.Overall, the SLC9A7 Antibody is a valuable tool for investigating the role of SLC9A7 in cellular processes and disease pathogenesis, making it a valuable asset for studies in molecular biology, biochemistry, and biomedicine.

Antibody Name:SLC9A7 Antibody (PACO18908)
Antibody SKU:PACO18908
Size:50ul
Host Species:Rabbit
Tested Applications:ELISA, IHC
Recommended Dilutions:ELISA:1:2000-1:5000, IHC:1:50-1:200
Species Reactivity:Human, Mouse
Immunogen:Synthetic peptide of human SLC9A7
Form:Liquid
Storage Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:Antigen affinity purification
Clonality:Polyclonal
Isotype:IgG
Conjugate:Non-conjugated
Product ImageThe image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using PACO18908(SLC9A7 Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: x200).
Background:This gene encodes a sodium and potassium/ proton antiporter that is a member of the solute carrier family 9 protein family. The encoded protein is primarily localized to the trans-Golgi network and is involved in maintaining pH homeostasis in organelles along the secretory and endocytic pathways. This protein may enhance cell growth of certain breast tumors. This gene is part of a gene cluster on chromosome Xp11.23. A pseudogene of this gene is found on chromosome 12. Alternate splicing results in multiple transcript variants.
Synonyms:solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7
UniProt Protein Function:SOX8: May play a role in central nervous system, limb and facial development. May be involved in male sex determination. Binds the consensus motif 5'-[AT][AT]CAA[AT]G-3'.Protein type: DNA-bindingChromosomal Location of Human Ortholog: 16p13.3Cellular Component: cytoplasm; nucleusMolecular Function: DNA binding; protein heterodimerization activity; transcription factor bindingBiological Process: negative regulation of photoreceptor cell differentiation; transcription from RNA polymerase II promoter; fat cell differentiation; cell fate commitment; positive regulation of gliogenesis; in utero embryonic development; astrocyte fate commitment; positive regulation of transcription, DNA-dependent; male gonad development; cell maturation; signal transduction; Sertoli cell development; enteric nervous system development; peripheral nervous system development; osteoblast differentiation; retina development in camera-type eye; positive regulation of osteoblast proliferation; oligodendrocyte differentiation; spermatogenesis; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; negative regulation of myoblast differentiation; neural crest cell migration; negative regulation of apoptosis
UniProt Protein Details:
NCBI Summary:This gene encodes a sodium and potassium/ proton antiporter that is a member of the solute carrier family 9 protein family. The encoded protein is primarily localized to the trans-Golgi network and is involved in maintaining pH homeostasis in organelles along the secretory and endocytic pathways. This protein may enhance cell growth of certain breast tumors. This gene is part of a gene cluster on chromosome Xp11.23. A pseudogene of this gene is found on chromosome 12. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2012]
UniProt Code:Q96T83
NCBI GenInfo Identifier:14211919
NCBI Gene ID:84679
NCBI Accession:NP_115980.1
UniProt Secondary Accession:Q96T83,O75827, Q5JXP9
UniProt Related Accession:Q96T83
Molecular Weight:80,131 Da
NCBI Full Name:sodium/hydrogen exchanger 7 isoform 2
NCBI Synonym Full Names:solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7
NCBI Official Symbol:SLC9A7  
NCBI Official Synonym Symbols:NHE7; NHE-7; SLC9A6  
NCBI Protein Information:sodium/hydrogen exchanger 7; Na(+)/H(+) exchanger 7; nonselective sodium potassium/proton exchanger; solute carrier family 9 (sodium/hydrogen exchanger), isoform 7
UniProt Protein Name:Transcription factor SOX-8
UniProt Synonym Protein Names:
Protein Family:Transcription factor
UniProt Gene Name:SOX8  
UniProt Entry Name:SOX8_HUMAN
Antibodies
SLC9A7 Antibody (PACO05534)
Secondary Antibody
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014)
Recommended Products
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011)
Anti-HRP-conjugated Beta Actin Antibody (CABC028)

Related Products