The SLC9A3R2 Polyclonal Antibody (CAB17591) is a valuable tool for researchers studying SLC9A3R2, a member of the solute carrier family known for its role in ion transport and cellular homeostasis. This antibody, produced in rabbits, exhibits high specificity and reactivity towards human samples, making it an essential component for Western blot applications. By binding to the SLC9A3R2 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it an ideal choice for studies in molecular biology and cell physiology.
SLC9A3R2, also known as NHE-RF2, is a key regulator of ion exchange and pH control within cells, playing a crucial role in maintaining cellular function and integrity. Dysregulation of SLC9A3R2 is associated with various diseases, including cancer and cardiovascular disorders, making it a promising target for therapeutic interventions. Research into the function and regulation of SLC9A3R2 is essential for advancing our understanding of these diseases and developing targeted treatments to improve patient outcomes.
Product Name:
SLC9A3R2 Rabbit Polyclonal Antibody
SKU:
CAB17591
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 180-300 of human SLC9A3R2 (NP_001123484).
This gene encodes a member of the NHERF family of PDZ scaffolding proteins. These proteins mediate many cellular processes by binding to and regulating the membrane expression and protein-protein interactions of membrane receptors and transport proteins. The encoded protein plays a role in intestinal sodium absorption by regulating the activity of the sodium/hydrogen exchanger 3, and may also regulate the cystic fibrosis transmembrane regulator (CFTR) ion channel. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Purification Method:
Affinity purification
Gene ID:
9351
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from HeLa cells, using SLC9A3R2 Rabbit pAb (CAB17591) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
