SLC9A3R1 Rabbit Polyclonal Antibody (CAB0146)
- SKU:
- CAB0146
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
Product Name: | SLC9A3R1 Rabbit Polyclonal Antibody |
SKU: | CAB0146 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 189-358 of human SLC9A3R1 (NP_004243.1). |
Sequence: | EASG LRAQ DRIV EVNG VCME GKQH GDVV SAIR AGGD ETKL LVVD RETD EFFK KCRV IPSQ EHLN GPLP VPFT NGEI QKEN SREA LAEA ALES PRPA LVRS ASSD TSEE LNSQ DSPP KQDS TAPS STSS SDPI LDFN ISLA MAKE RAHQ KRSS KRAP QMDW SKKN ELFS NL |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:1000 - 1:4000 |
Synonyms: | EBP50; NHERF; NHE-RF; NHERF-1; NPHLOP2; SLC9A3R1 |
Positive Sample: | HepG2,293T,HT-29,MCF7,Mouse liver,Mouse kidney,Rat liver |
Conjugate: | Unconjugated |
Cellular Localization: | Apical cell membrane, Cell projection, Cytoplasm, Endomembrane system, Peripheral membrane protein, filopodium, microvillus, ruffle. |
Calculated MW: | 39kDa |
Observed MW: | 50kDa |
This gene encodes a sodium/hydrogen exchanger regulatory cofactor. The protein interacts with and regulates various proteins including the cystic fibrosis transmembrane conductance regulator and G-protein coupled receptors such as the beta2-adrenergic receptor and the parathyroid hormone 1 receptor. The protein also interacts with proteins that function as linkers between integral membrane and cytoskeletal proteins. The protein localizes to actin-rich structures including membrane ruffles, microvilli, and filopodia. Mutations in this gene result in hypophosphatemic nephrolithiasis/osteoporosis type 2, and loss of heterozygosity of this gene is implicated in breast cancer.
Purification Method: | Affinity purification |
Gene ID: | 9368 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |