The SLC9A3 Polyclonal Antibody (CAB17532) is specifically designed for research involving SLC9A3, a sodium/hydrogen exchanger protein that plays a crucial role in regulating cellular pH and ion balance. The antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications.SLC9A3 is involved in a variety of physiological processes, including cell growth, migration, and apoptosis, making it a key player in cancer progression and metastasis. Studies have shown that dysregulation of SLC9A3 expression is associated with various diseases, including cancer, cardiovascular disorders, and neurological conditions.
The SLC9A3 Polyclonal Antibody binds specifically to the SLC9A3 protein, enabling researchers to detect and study its expression levels in different cell types and tissues. This antibody is an essential tool for investigating the role of SLC9A3 in cellular signaling pathways, disease pathology, and potential therapeutic interventions in various research fields, including cancer biology and molecular medicine.
Product Name:
SLC9A3 Rabbit Polyclonal Antibody
SKU:
CAB17532
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 460-600 of human SLC9A3 (NP_004165.2).
The protein encoded by this gene is an epithelial brush border Na/H exchanger that uses an inward sodium ion gradient to expel acids from the cell. Defects in this gene are a cause of congenital secretory sodium diarrhea. Pseudogenes of this gene exist on chromosomes 10 and 22.
Purification Method:
Affinity purification
Gene ID:
6550
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from Rat kidney, using SLC9A3 Rabbit pAb (CAB17532) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 120s.
