The SLC8A2 Polyclonal Antibody (CAB15723) is a valuable tool for researchers studying SLC8A2, a protein involved in calcium signaling and transport. This antibody, produced in rabbits, has high reactivity with human samples and is specifically validated for use in Western blot applications. By binding to the SLC8A2 protein, this antibody allows for the detection and analysis of SLC8A2 expression in various cell types, making it an excellent choice for studies in the fields of cell biology and neuroscience.SLC8A2, also known as sodium/calcium exchanger 2, plays a crucial role in the regulation of intracellular calcium levels, impacting processes such as muscle contraction, neurotransmitter release, and cell signaling.
Dysregulation of SLC8A2 has been linked to various diseases, including cardiovascular disorders and neurological conditions. Therefore, investigating the function and regulation of SLC8A2 is essential for understanding the underlying mechanisms of these diseases and identifying potential therapeutic targets.
Product Name:
SLC8A2 Rabbit Polyclonal Antibody
SKU:
CAB15723
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 360-450 of human SLC8A2 (NP_055878.1).
Predicted to enable calcium:cation antiporter activity involved in regulation of postsynaptic cytosolic calcium ion concentration and calcium:sodium antiporter activity. Predicted to be involved in several processes, including inorganic cation transmembrane transport; learning or memory; and regulation of short-term neuronal synaptic plasticity. Predicted to act upstream of or within several processes, including modulation of chemical synaptic transmission; regulation of action potential firing pattern; and response to ischemia. Part of presynapse. Biomarker of Alzheimer's disease.
Purification Method:
Affinity purification
Gene ID:
6543
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using SLC8A2 Rabbit pAb (CAB15723) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
