The SLC7A8 Polyclonal Antibody (CAB14861) is a valuable tool for researchers studying SLC7A8, a member of the solute carrier family of membrane transport proteins. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the SLC7A8 protein, this antibody enables precise detection and analysis in various cell types, making it ideal for studies in transporter biology and metabolic research.SLC7A8 is known for its role in transporting amino acids across cell membranes, playing a crucial part in cellular metabolism and nutrient uptake.
Its function in amino acid transport makes it a key player in cellular physiology and has implications for metabolic disorders, nutrient deficiencies, and cancer metabolism. By investigating the activity of SLC7A8, researchers can gain insights into the molecular mechanisms underlying these conditions and potentially develop new therapeutic strategies targeting amino acid transport.
Product Name:
SLC7A8 Rabbit Polyclonal Antibody
SKU:
CAB14861
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 150-250 of human SLC7A8 (NP_036376.2).
Enables several functions, including neutral amino acid transmembrane transporter activity; thyroid hormone transmembrane transporter activity; and toxin transmembrane transporter activity. Involved in L-alanine import across plasma membrane; L-leucine import across plasma membrane; and thyroid hormone transport. Located in plasma membrane. Part of basolateral plasma membrane and microvillus membrane.
Purification Method:
Affinity purification
Gene ID:
23428
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using SLC7A8 Rabbit pAb (CAB14861) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
