The SLC7A5 Polyclonal Antibody (CAB2833) is a valuable tool for research involving the SLC7A5 protein, also known as L-type amino acid transporter 1 (LAT1), which plays a crucial role in the transportation of large neutral amino acids across the cell membrane. This antibody, generated in rabbits, is highly specific and reactive with human samples, making it ideal for use in various research applications, including Western blotting.SLC7A5/LAT1 is essential for the uptake of essential amino acids needed for protein synthesis and cell growth, making it a potential target in cancer research and metabolic disorders. Its overexpression has been linked to the growth and proliferation of cancer cells, making it a promising target for anti-cancer therapies.
By targeting SLC7A5, researchers aim to develop novel treatments for various types of cancer and metabolic diseases.This polyclonal antibody enables the detection and analysis of SLC7A5/LAT1 protein levels in different cell types, providing valuable insights into its role in amino acid transport and its implications in disease pathology. Understanding the function of SLC7A5 is crucial for identifying potential therapeutic targets and developing targeted therapies for cancer and metabolic disorders.
Product Name:
SLC7A5 Rabbit Polyclonal Antibody
SKU:
CAB2833
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-125 of human LAT1/SLC7A5 (NP_003477.4).
Enables L-leucine transmembrane transporter activity; L-tryptophan transmembrane transporter activity; and thyroid hormone transmembrane transporter activity. Involved in carboxylic acid transport; thyroid hormone transport; and xenobiotic transport. Located in cytosol; intracellular membrane-bounded organelle; and plasma membrane. Is integral component of membrane. Part of amino acid transport complex; apical plasma membrane; and microvillus membrane.
Purification Method:
Affinity purification
Gene ID:
8140
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of Mouse testis, using LAT1/SLC7A5 antibody (CAB2833) at 1:900 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
