The SLC7A14 Polyclonal Antibody (PACO39190) is a valuable tool for research focusing on SLC7A14, a crucial transporter protein involved in amino acid transport across cell membranes. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the SLC7A14 protein, this antibody enables accurate detection and analysis in various cell types, making it an essential component for studies in the fields of metabolism, nutrition, and cancer research.SLC7A14, also known as the solute carrier family 7 member 14 protein, plays a vital role in mediating the uptake of essential amino acids, such as arginine and lysine, into cells.
Its function is implicated in various physiological processes, including protein synthesis, cell growth, and immune response modulation. Research on SLC7A14 is essential for understanding nutrient transport mechanisms and their impact on cellular function, as well as for developing targeted therapies for metabolic disorders and cancer. This antibody provides researchers with a reliable tool for investigating the role of SLC7A14 in health and disease.
Antibody Name:
SLC7A14 Antibody (PACO39190)
Antibody SKU:
PACO39190
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:10000, IHC:1:20-1:200
Species Reactivity:
Human
Immunogen:
Recombinant Human Probable cationic amino acid, transporter protein (676-771AA)
Immunohistochemistry of paraffin-embedded human prostate cancer using PACO39190 at dilution of 1:100.
Background:
May be involved in arginine transport.
Synonyms:
Probable cationic amino acid, transporter (Solute carrier family 7 member 14), SLC7A14, KIAA1613
UniProt Protein Function:
May be involved in arginine transport.
UniProt Protein Details:
NCBI Summary:
This gene is predicted to encode a glycosylated, cationic amino acid transporter protein with 14 transmembrane domains. This gene is primarily expressed in skin fibroblasts, neural tissue, and primary endothelial cells and its protein is predicted to mediate lysosomal uptake of cationic amino acids. Mutations in this gene are associated with autosomal recessive retinitis pigmentosa. In mice, this gene is expressed in the photoreceptor layer of the retina where its expression increases over the course of retinal development and persists in the mature retina. [provided by RefSeq, Apr 2014]
