SLC7A11/xCT Rabbit Polyclonal Antibody (CAB13685)
- SKU:
- CAB13685
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
Product Name: | SLC7A11/xCT Rabbit Polyclonal Antibody |
SKU: | CAB13685 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human SLC7A11/xCT (NP_055146.1). |
Sequence: | MVRK PVVS TISK GGYL QGNV NGRL PSLG NKEP PGQE KVQL KRKV TLLR GVSI IIGT IIGA GIFI SPKG VLQN TGSV GMSL TIWT VCGV LSLF GALS YAEL |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:1000 - 1:5000 |
Synonyms: | xCT; CCBR1; SLC7A11/xCT |
Positive Sample: | Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Membrane, Multi-pass membrane protein. |
Calculated MW: | 55kDa |
Observed MW: | 55kDa |
This gene encodes a member of a heteromeric, sodium-independent, anionic amino acid transport system that is highly specific for cysteine and glutamate. In this system, designated Xc(-), the anionic form of cysteine is transported in exchange for glutamate. This protein has been identified as the predominant mediator of Kaposi sarcoma-associated herpesvirus fusion and entry permissiveness into cells. Also, increased expression of this gene in primary gliomas (compared to normal brain tissue) was associated with increased glutamate secretion via the XCT channels, resulting in neuronal cell death.
Purification Method: | Affinity purification |
Gene ID: | 23657 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |