The SLC6A7 Antibody (PAC020526) is a valuable tool for research involving the SLC6A7 protein, a neurotransmitter transporter involved in the regulation of neurotransmitter concentrations in the brain. This polyclonal antibody, produced in rabbits, exhibits high reactivity towards human samples and has been validated for use in Western blot applications. By binding specifically to the SLC6A7 protein, this antibody enables accurate detection and analysis in various cell types, making it an ideal choice for studies in neuroscience and neurology research.SLC6A7, also known as the neurotransmitter transporter GlyT1, plays a crucial role in maintaining neurotransmitter levels in the central nervous system, particularly glycine.
Dysregulation of SLC6A7 function has been implicated in various neurological disorders, such as schizophrenia and epilepsy. By investigating the activity of SLC6A7, researchers can gain valuable insights into the mechanisms underlying these conditions and potentially identify new therapeutic targets for treatment.Overall, the SLC6A7 Antibody (PAC020526) is a valuable tool for researchers studying neurotransmitter transporters and their role in neurological health and disease. Its high specificity and sensitivity make it a reliable option for Western blot experiments, providing valuable data for advancing our understanding of the neurobiology of various neurological disorders.
Antibody Name:
SLC6A7 Antibody (PACO20526)
Antibody SKU:
PACO20526
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:1000-1:2000, IHC:1:25-1:100
Species Reactivity:
Human, Rat
Immunogen:
Synthetic peptide of human SLC6A7
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using PACO20526(SLC6A7 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200).
Background:
This gene is a member of the gamma-aminobutyric acid, (GABA) neurotransmitter gene family and encodes a high-affinity mammalian brain L-proline transporter protein. This transporter protein differs from other sodium-dependent plasma membrane carriers by its pharmacological specificity, kinetic properties, and ionic requirements.
Synonyms:
solute carrier family 6 (neurotransmitter transporter), member 7
UniProt Protein Function:
Terminates the action of proline by its high affinity sodium-dependent reuptake into presynaptic terminals.
UniProt Protein Details:
NCBI Summary:
This gene is a member of the gamma-aminobutyric acid (GABA) neurotransmitter gene family and encodes a high-affinity mammalian brain L-proline transporter protein. This transporter protein differs from other sodium-dependent plasma membrane carriers by its pharmacological specificity, kinetic properties, and ionic requirements. [provided by RefSeq, Jul 2008]
