Serotonin transporter Rabbit Polyclonal Antibody (CAB14171)
- SKU:
- CAB14171
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Neuroscience
Frequently bought together:
Description
Product Name: | Serotonin transporter Rabbit Polyclonal Antibody |
SKU: | CAB14171 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-84 of human Serotonin transporter (NP_001036.1). |
Sequence: | METT PLNS QKQL SACE DGED CQEN GVLQ KVVP TPGD KVES GQIS NGYS AVPS PGAG DDTR HSIP ATTT TLVA ELHQ GERE TWGK |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:100 - 1:500 IHC-P,1:50 - 1:200 |
Synonyms: | HTT; 5HTT; OCD1; SERT; 5-HTT; SERT1; hSERT; 5-HTTLPR; Serotonin transporter |
Positive Sample: | Rat lung |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Endomembrane system, Endosome membrane, Multi-pass membrane protein. |
Calculated MW: | 70kDa |
Observed MW: | 75kDa |
This gene encodes an integral membrane protein that transports the neurotransmitter serotonin from synaptic spaces into presynaptic neurons. The encoded protein terminates the action of serotonin and recycles it in a sodium-dependent manner. This protein is a target of psychomotor stimulants, such as amphetamines and cocaine, and is a member of the sodium:neurotransmitter symporter family. A repeat length polymorphism in the promoter of this gene has been shown to affect the rate of serotonin uptake. There have been conflicting results in the literature about the possible effect, if any, that this polymorphism may play in behavior and depression.
Purification Method: | Affinity purification |
Gene ID: | 6532 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |