The SLC6A16 Polyclonal Antibody (PACO03969) is a valuable tool for researchers studying SLC6A16, a member of the solute carrier family of proteins involved in neurotransmitter transport and metabolism. This antibody, developed using rabbits, exhibits high specificity and sensitivity towards human samples and is validated for use in Western blotting applications.SLC6A16, also known as sodium- and chloride-dependent creatine transporter 2, plays a key role in the uptake and transport of creatine in cells, influencing energy metabolism and muscle function.
Its involvement in creatine homeostasis makes it a promising target for investigations into conditions related to energy balance, muscle disorders, and neurodegenerative diseases.By facilitating the detection and analysis of SLC6A16 protein expression in various cell types, this antibody provides researchers with valuable insights into the physiological and pathological functions of SLC6A16. Its utility in both basic research and drug development makes it an essential tool for studies exploring the role of SLC6A16 in health and disease.
Antibody Name:
SLC6A16 Antibody
Antibody SKU:
PACO03969
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
IHC:1:100-1:300
Species Reactivity:
Human
Immunogen:
synthesized peptide derived from the Internal region of human NTT5.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
SLC6A16; NTT5; Orphan sodium- and chloride-dependent neurotransmitter transporter NTT5; Solute carrier family 6 member 16
UniProt Protein Function:
SLC6A16: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A16 subfamilyProtein type: Transporter; Transporter, SLC family; Membrane protein, integral; Membrane protein, multi-passChromosomal Location of Human Ortholog: 19q13.33Cellular Component: integral to membrane; intracellularMolecular Function: neurotransmitter:sodium symporter activity; neurotransmitter transporter activityBiological Process: neurotransmitter transport; transmembrane transport
UniProt Protein Details:
NCBI Summary:
SLC6A16 shows structural characteristics of an Na(+)- and Cl(-)-dependent neurotransmitter transporter, including 12 transmembrane (TM) domains, intracellular N and C termini, and large extracellular loops containing multiple N-glycosylation sites.[supplied by OMIM, Mar 2008]
