The SLC6A14 Polyclonal Antibody (CAB10582) is specifically designed for research involving SLC6A14, a cell surface transporter protein that plays a crucial role in amino acid uptake regulation. This antibody, produced through rabbit immunization, exhibits high reactivity with human samples and is validated for use in Western blot applications. It effectively binds to the SLC6A14 protein, enabling accurate detection and analysis in various cell types, making it an ideal tool for studies in biochemistry and cancer research.
SLC6A14, also known as Na+/Cl- dependent neutral and basic amino acid transporter B(0,+), is essential for maintaining cellular amino acid homeostasis and supporting nutrient uptake processes. Its significance in amino acid transport regulation makes it a valuable target for research into various metabolic disorders and cancer progression. The thorough exploration of SLC6A14 function is crucial for advancing the development of therapies that target amino acid metabolism in disease contexts.
Product Name:
SLC6A14 Rabbit Polyclonal Antibody
SKU:
CAB10582
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 131-234 of human SLC6A14 (NP_009162.1).
HeLa,HepG2,MCF7,BxPC-3,Mouse large intestine,Mouse lung,Mouse testis
Conjugate:
Unconjugated
Cellular Localization:
Membrane, Multi-pass membrane protein.
Calculated MW:
72kDa
Observed MW:
72kDa
This gene encodes a member of the solute carrier family 6. Members of this family are sodium and chloride dependent neurotransmitter transporters. The encoded protein transports both neutral and cationic amino acids. This protein may also function as a beta-alanine carrier. Mutations in this gene may be associated with X-linked obesity. A pseudogene of this gene is found on chromosome X.
Purification Method:
Affinity purification
Gene ID:
11254
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using SLC6A14 antibody (CAB10582) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
