The SLC6A13 Polyclonal Antibody (PAC052866) is a valuable tool for researchers studying SLC6A13, a member of the SLC6 family of neurotransmitter transporters. This antibody, produced in rabbits, has high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the SLC6A13 protein, this antibody allows for the detection and analysis of SLC6A13 in a variety of cell types, making it ideal for studies in neuroscience and pharmacology.SLC6A13 is a transporter protein that plays a crucial role in the reuptake of neurotransmitters, particularly in the central nervous system.
Its function in regulating neurotransmitter levels makes it a promising target for research into neurological disorders, such as epilepsy, depression, and anxiety. By investigating the activity of SLC6A13, researchers can gain valuable insights into the mechanisms underlying these conditions and potentially develop new therapeutic strategies for treating them.
Western Blot. Positive WB detected in: Mouse heart tissue, Mouse brain tissue, Mouse kidney tissue. All lanes: SLC6A13 antibody at 3µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 69, 58, 11 kDa. Observed band size: 69 kDa.
Immunohistochemistry of paraffin-embedded human kidney tissue using PACO52866 at dilution of 1:100.
Immunohistochemistry of paraffin-embedded human testis tissue using PACO52866 at dilution of 1:100.
Background:
Sodium-dependent GABA and taurine transporter. In presynaptic terminals, regulates GABA signaling termination through GABA uptake. May also be involved in beta-alanine transport.
Synonyms:
Sodium- and chloride-dependent GABA transporter 2 (GAT-2) (Solute carrier family 6 member 13), SLC6A13, GAT2
UniProt Protein Function:
Sodium-dependent GABA and taurine transporter. In presynaptic terminals, regulates GABA signaling termination through GABA uptake. May also be involved in beta-alanine transport.
