The SLC6A1 Polyclonal Antibody (CAB15099) is an essential tool for researchers studying the SLC6A1 protein, which is a member of the neurotransmitter sodium symporter family. This antibody is produced in rabbits and has been rigorously tested for its reactivity with human samples, making it suitable for Western blot applications. By binding specifically to the SLC6A1 protein, this antibody allows for the precise detection and analysis of SLC6A1 in a variety of cell types.SLC6A1, also known as the GABA transporter 1, is involved in the reuptake of the neurotransmitter gamma-aminobutyric acid (GABA) in the central nervous system. Dysregulation of SLC6A1 has been linked to neurological disorders such as epilepsy and autism spectrum disorders.
Research on SLC6A1 is essential for understanding the pathophysiology of these conditions and developing targeted therapies.With its high specificity and reactivity with human samples, the SLC6A1 Polyclonal Antibody (CAB15099) is a valuable tool for researchers in the fields of neuroscience, neurology, and psychiatry. By enabling the accurate detection and analysis of SLC6A1, this antibody contributes to advancements in our understanding of neurotransmitter transport and its implications for brain function and neurological health.
Product Name:
SLC6A1 Rabbit Polyclonal Antibody
SKU:
CAB15099
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 500-599 of human SLC6A1 (NP_003033.3).
The protein encoded by this gene is a gamma-aminobutyric acid (GABA) transporter that localizes to the plasma membrane. The encoded protein removes GABA from the synaptic cleft, restoring it to presynaptic terminals.
Purification Method:
Affinity purification
Gene ID:
6529
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using SLC6A1 Rabbit pAb (CAB15099) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
