The SLC5A11 Polyclonal Antibody (CAB13164) is a valuable tool for researchers investigating the SLC5A11 protein, which is a member of the solute carrier family known for its role in glucose absorption and metabolism. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in Western blotting applications.SLC5A11 is involved in the transport of glucose and other sugars across cell membranes, making it a key player in maintaining glucose homeostasis in the body. Dysregulation of SLC5A11 function has been implicated in various metabolic disorders, such as diabetes and obesity, making it an important target for research in the field of metabolism and nutrition.
By using the SLC5A11 Polyclonal Antibody, researchers can accurately detect and analyze the expression of SLC5A11 in different cell types and tissues, providing valuable insights into its role in glucose transport and metabolism. This antibody is essential for studies aimed at understanding the mechanisms underlying metabolic diseases and developing potential therapeutic interventions.
Product Name:
SLC5A11 Rabbit Polyclonal Antibody
SKU:
CAB13164
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 540-640 of human SLC5A11 (NP_443176.2).
Sequence:
SWFT EPPS KEMV SHLT WFTR HDPV VQKE QAPP AAPL SLTL SQNG MPEA SSSS SVQF EMVQ ENTS KTHS CDMT PKQS KVVK AILW LCGI QEKG KEEL PARA E
Tested Applications:
WBELISA
Recommended Dilution:
WB,1:500 - 1:2000
Synonyms:
KST1; RKST1; SGLT6; SMIT2; SLC5A11
Positive Sample:
293T,U-87MG,Mouse kidney,Rat brain
Conjugate:
Unconjugated
Cellular Localization:
Membrane, Multi-pass membrane protein.
Calculated MW:
74kDa
Observed MW:
74kDa
Cotransporters, such as SLC5A11, represent a major class of proteins that make use of ion gradients to drive active transport for the cellular accumulation of nutrients, neurotransmitters, osmolytes, and ions Roll et al. (2002) [PubMed 12039040].
Purification Method:
Affinity purification
Gene ID:
115584
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using SLC5A11 Rabbit pAb (CAB13164) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
