The SLC5A10 Polyclonal Antibody (PAC029968) is a vital tool for researchers studying SLC5A10, a key protein involved in sodium-dependent glucose transport. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in applications such as Western blot analysis. By binding specifically to SLC5A10, this antibody allows for accurate detection and analysis of the protein in various cell types, making it an excellent choice for studies in biochemistry and physiology.
SLC5A10, a member of the sodium-glucose cotransporter family, plays a crucial role in glucose absorption and homeostasis in the body. Its involvement in the transport of glucose across cell membranes makes it a promising target for research into metabolic disorders, diabetes, and other related conditions. By gaining a better understanding of the function and regulation of SLC5A10, researchers can further advance their knowledge of glucose metabolism and potentially develop new treatments for associated diseases.
Immunofluorescent analysis of Hela cells using PACO29968 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Immunohistochemistry of paraffin-embedded human salivary gland tissue using PACO29968 at dilution of 1:100.
Immunohistochemistry of paraffin-embedded human skeletal muscle tissue using PACO29968 at dilution of 1:100.
Background:
High capacity transporter for mannose and fructose and, to a lesser extent, glucose, AMG, and galactose.
Synonyms:
Sodium/glucose cotransporter 5 (Na(+)/glucose cotransporter 5) (Solute carrier family 5 member 10), SLC5A10, SGLT5
UniProt Protein Function:
High capacity transporter for mannose and fructose and, to a lesser extent, glucose, AMG, and galactose.
UniProt Protein Details:
NCBI Summary:
This gene is a member of the sodium/glucose transporter family. Members of this family are sodium-dependent transporters and can be divided into two subfamilies based on sequence homology, one that co-transports sugars and the second that transports molecules such as ascorbate, choline, iodide, lipoate, monocaroboxylates, and pantothenate. The protein encoded by this gene has the highest affinity for mannose and has been reported to be most highly expressed in the kidney. This protein may function as a kidney-specific, sodium-dependent mannose and fructose co-transporter. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Jul 2012]
