The SLC5A1 Polyclonal Antibody (CAB11976) is a vital tool for researchers studying SLC5A1, a sodium-dependent glucose transporter protein involved in glucose uptake and renal reabsorption. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By targeting the SLC5A1 protein, researchers can accurately detect and analyze its expression in various cell types, making it a valuable asset for studies in physiology and metabolic disorders.
SLC5A1 is a key player in glucose homeostasis, playing a crucial role in maintaining blood glucose levels and overall metabolic health. Dysregulation of SLC5A1 has been linked to conditions such as diabetes and obesity, making it a promising target for therapeutic interventions. Investigating the function of SLC5A1 with this antibody can provide insights into its role in glucose metabolism and offer potential avenues for treating glucose-related disorders.
Product Name:
SLC5A1 Rabbit Polyclonal Antibody
SKU:
CAB11976
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 400-500 of human SLC5A1 (NP_000334.1).
Sequence:
DIYA KVRK RASE KEL
Tested Applications:
WBELISA
Recommended Dilution:
WB,1:500 - 1:1000
Synonyms:
NAGT; SGLT1; SGLT-1; D22S675; SLC5A1
Positive Sample:
293F
Conjugate:
Unconjugated
Cellular Localization:
Membrane, Multi-pass membrane protein.
Calculated MW:
73kDa
Observed MW:
74kDa
This gene encodes a member of the sodium-dependent glucose transporter (SGLT) family. The encoded integral membrane protein is the primary mediator of dietary glucose and galactose uptake from the intestinal lumen. Mutations in this gene have been associated with glucose-galactose malabsorption. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
6523
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of 293F, using SLC5A1 Rabbit pAb (CAB11976) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 45s.
