The SLC52A3 Polyclonal Antibody (CAB15935) is a valuable tool for researchers studying the SLC52A3 protein, which plays a key role in the transport of riboflavin (Vitamin B2) into cells. This antibody, produced in rabbits, exhibits high specificity for human samples and is suitable for use in Western blot applications. By binding to the SLC52A3 protein, this antibody allows for the detection and analysis of SLC52A3 expression in various cell types, making it an essential component for studies in metabolism, nutrient transport, and vitamin biology.SLC52A3 is a transmembrane protein essential for riboflavin uptake, a crucial step in cellular energy production and metabolism.
Research on SLC52A3 is important for understanding the mechanisms of nutrient uptake and utilization in cells, with potential implications for metabolic disorders, vitamin deficiencies, and energy metabolism. By targeting SLC52A3 with this antibody, researchers can gain insights into the functions and regulation of this vital transporter, advancing our knowledge of cellular nutrient homeostasis and potential therapeutic interventions.
Product Name:
SLC52A3 Rabbit Polyclonal Antibody
SKU:
CAB15935
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 200-300 of human SLC52A3 (NP_212134.3).
This gene encodes a riboflavin transporter protein that is strongly expressed in the intestine and likely plays a role in intestinal absorption of riboflavin. The protein is predicted to have eleven transmembrane domains and a cell surface localization signal in the C-terminus. Mutations at this locus have been associated with Brown-Vialetto-Van Laere syndrome and Fazio-Londe disease.
Purification Method:
Affinity purification
Gene ID:
113278
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from mouse kidney, using SLC52A3 Rabbit pAb (CAB15935) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
